Transition‐Metal‐Free C(sp2)−H Phosphorothiolation/Cyclization of o‐Hydroxyarylenaminones: Access to S‐3‐Chromon Phosphorothioates. Issue 9 (29th March 2022)

• Record Type: Journal Article
• Authors: Zhang, Biao; Fu, Zhonghui; Yang, Haoqi; Liu, Donghan; Sun, Yulin; Xu, Yu; Yu, Fuchao; Yan, Sheng‐Jiao
• Is Part Of: Advanced synthesis & catalysis. Volume 364:Issue 9(2022)
• Page Start: 1602
• Page End: 1606
• Publication Date: 2022-03-29
• Subjects: Phosphorothiolation -- o-Hydroxyarylenaminones -- S-3-Chromon phosphorothioates -- Transition-metal-free; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202200089
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: The C( sp 2 )−H phosphorothiolation involving cyclization process through a transition‐metal‐free strategy is reported. It provides an attractive approach for the construction valuable S ‐3‐chromon phosphorothioates from o ‐hydroxyarylenaminones and P(O)SH compounds in the presence of 1.0 equiv. of iodine at 60 °C. This novel protocol shows readily available chemicals, broad substrate scope, and mild reaction conditions. Abstract :