Five new Erythrina alkaloids from the stems of Erythrina corallodendron. Issue 5 (4th May 2022)

• Record Type: Journal Article
• Authors: Cai, Yun-Shuang; Li, Yu-Tong; Fu, Jiang; Chen, Zhao-Chan; Wang, Yang; Li, Yong; Yu, Shi-Shan
• Is Part Of: Journal of Asian natural products research. Volume 24:Issue 5(2022)
• Page Start: 457
• Page End: 467
• Publication Date: 2022-05-04
• Subjects: Erythrina corallodendron -- Erythrina alkaloid -- antinociceptive activity; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2021.2025050
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Five new Erythrina alkaloids and five known E. alkaloids were isolated from a 95% ethanol extract of the stems of Erythrina corallodendron L. Their chemical structures were elucidated by UV, IR, HRESIMS, NMR and X-ray. Furthermore, the analgesic activities of E. alkaloids 1, 2 and 6 were evaluated by using an acetic acid-induced writhing test in mice, and their writhing inhibition rates were 67.9%, 64.6% and 70.3% at doses of 20 mg/kg, respectively. Graphical Abstract: UF0001