Tf2O‐Mediated Regioselective C(sp2)−H Sulfenylation of Enaminones Using Methyl Sulfoxides as Sulfur Sources. Issue 4 (11th March 2022)

• Record Type: Journal Article
• Authors: Zhang, Changyuan; Luo, Jian; Zhang, Jiantao; Chen, Lulu; Zhu, Xuncheng; Guo, Mengping; Shen, Chan; Li, Zeng; Wang, Wei
• Is Part Of: Asian journal of organic chemistry. Volume 11:Issue 4(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-03-11
• Subjects: β-Amino sulfides -- enaminones -- methyl sulfoxides -- one-pot manner -- sulfenylation; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.202200014
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: An efficient Tf2 O‐mediated regioselective C(sp 2 )−H sulfenylation of enaminones has been described. Methyl sulfoxides are employed as sulfur sources to react with different types of enaminones under mild reaction conditions, providing a straightforward approach for the synthesis of β‐amino sulfides in up to 97% yield via one‐pot manner. Moreover, this sulfenylation proceeded smoothly with oxidant‐free and metal‐free. Abstract : An efficient Tf2 O‐mediated regioselective C(sp 2 )−H sulfenylation of enaminones has been described. Methyl sulfoxides are employed as sulfur sources to react with different types of enaminones under mild reaction conditions, providing a straightforward approach for the synthesis of β‐amino sulfides in up to 97% yield via one‐pot manner. Moreover, this sulfenylation proceeded smoothly with oxidant‐free and metal‐free.