Secondary metabolites with diversified structures from an endophytic fungus Colletotrichum gloeosporioides associated with a toxic medicinal plant Tylophora ovata. Issue 5 (4th May 2022) - Sun, Sen-Feng
Abstract: Six new secondary metabolites, including two new nor-triterpenes (1 and 2 ), one new sesquiterpene (4 ), two new α -pyrone derivatives (6 and 7 ), and one new natural product (5 ) along with two known compounds (3 and 8 ) were isolated from an endophytic fungus Colletotrichum gloeosporioides obtained from a toxic medicinal plant Tylophora ovata . Their structures were elucidated by spectroscopic data analyses, while their absolute configurations were determined by CD and X-ray diffraction analyses. The in vitro anti-inflammatory activities of these compounds were evaluated. Graphical Abstract: UF0001