Electrochemiluminescence of Ru(bpy)32+/thioacetamide and its application for the sensitive determination of hepatotoxic thioacetamide. Issue 16 (26th July 2021)

• Record Type: Journal Article
• Authors: Kitte, Shimeles Addisu; Bushira, Fuad Abduro; Li, Haijuan; Jin, Yongdong
• Is Part Of: Analyst. Volume 146:Issue 16(2021)
• Page Start: 5198
• Page End: 5203
• Publication Date: 2021-07-26
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/d1an00862e
• Languages: English
• ISSNs: 0003-2654

Abstract

Abstract : A new ECL sensor for the sensitive determination of thioacetamide was developed using thioacetamide as a coreactant for the anodic ECL of tris(2, 2′-bipyridyl)ruthenium(ii ) (Ru(bpy)3 2+ ). Abstract : Thioacetamide (TAA) is a well-known hepatotoxic substance, so it is important to determine its presence and content in food and environmental samples. Herein, we report a highly sensitive determination method for TAA based on the electrochemiluminescence (ECL) of tris(2, 2′-bipyridyl)ruthenium(ii ) (Ru(bpy)3 2+ ) for the first time by using TAA as a new coreactant for Ru(bpy)3 2+ ECL via an anodic route. The developed Ru(bpy)3 2+ –TAA ECL system allows the determination of TAA with a good dynamic linear range and low limit of detection (LOD) of 0.1 μM to 1000 μM and 0.035 μM (3 σ / m ), respectively. In addition, the established ECL system can be applied to detect TAA in fruit juice and waste water samples with outstanding recoveries.