Promoting high T2 contrast in Dy-doped MSNs through Curie effects. Issue 2 (16th December 2021)

• Record Type: Journal Article
• Authors: Ellis, Connor M.; Pellico, Juan; Young, Liam A. J.; Miller, Jack; Davis, Jason J.
• Is Part Of: Journal of materials chemistry. Volume 10:Issue 2(2021)
• Page Start: 302
• Page End: 305
• Publication Date: 2021-12-16
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/d1tb01894a
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : The dominant Curie effect underpinning relaxivity enhancements in T 2 has been systematically tuned through paramagnetic loading density. This results in the optimisation of acquired MR image contrast, and facilitates effective high field imaging. Abstract : Contrast agents retaining high relaxivities at ultrahigh magnetic fields underpin an enhanced image sensitivity within derived MRI scans. By varying the Dy 3+ loading density inside a mesoporous silica architecture the dominant Curie effect can be effectively tuned so as to optimise T 2 contrast at magnetic fields as high as 11.7 T.