Characterization of a class II ketol-acid reductoisomerase from Mycobacterium tuberculosis. Issue 17 (6th April 2022)
- Record Type:
- Journal Article
- Title:
- Characterization of a class II ketol-acid reductoisomerase from Mycobacterium tuberculosis. Issue 17 (6th April 2022)
- Main Title:
- Characterization of a class II ketol-acid reductoisomerase from Mycobacterium tuberculosis
- Authors:
- Valera, Ane
Wang, Shan
Carr, Reuben
Trembleau, Laurent
Deng, Hai - Abstract:
- Abstract : Biochemical characterization of an unusual class II KARI (MtKARI-II) from a Mycobacterium tuberculosis variant. Abstract : Mycobacterium tuberculosis ketol-acid reductoisomerases have been widely studied due to their metabolic importance towards development of drug-resistant bacteria treatment. We here report the biochemical characterization of a new KARI (MtKARI-II) from a Mycobacterium tuberculosis variant with a similar kinetic profile to class I KARIs. Phylogenetic analysis suggested that MtKARI-II is clustered into a class II KARI superfamily.
- Is Part Of:
- RSC advances. Volume 12:Issue 17(2022)
- Journal:
- RSC advances
- Issue:
- Volume 12:Issue 17(2022)
- Issue Display:
- Volume 12, Issue 17 (2022)
- Year:
- 2022
- Volume:
- 12
- Issue:
- 17
- Issue Sort Value:
- 2022-0012-0017-0000
- Page Start:
- 10540
- Page End:
- 10544
- Publication Date:
- 2022-04-06
- Subjects:
- Chemistry -- Periodicals
540.5 - Journal URLs:
- http://pubs.rsc.org/en/Journals/JournalIssues/RA ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d1ra08876a ↗
- Languages:
- English
- ISSNs:
- 2046-2069
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8036.750300
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 21415.xml