Co-Catalyzed C(sp3)–C(sp2) bond cleavage via hydrogen atom transfer. Issue 8 (15th March 2022)

• Record Type: Journal Article
• Authors: Zhou, Bingqing; Tian, Di; An, Jinglin; Zhou, Yalan; Yan, Rui; Song, Hao; Liu, Xiao-Yu; Qin, Yong
• Is Part Of: Organic chemistry frontiers. Volume 9:Issue 8(2022)
• Page Start: 2135
• Page End: 2140
• Publication Date: 2022-03-15
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d2qo00125j
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A new HAT-initiated C(sp 3 )–C(sp 2 ) bond cleavage approach enabling the functionalization of alkenes to ketones is presented. Abstract : The discovery of a new Co-catalyzed hydrogen atom transfer (HAT) C(sp 3 )–C(sp 2 ) bond cleavage method to access ketones from alkenes is reported. This unprecedented transformation features mild reaction conditions and good functional group compatibility, and it proceeds through a key alkoxy radical formation and subsequent β-fragmentation approach.