A novel fast-responsive fluorescent probe based on 1, 3, 5-triazine for endogenous H2S detection with large Stokes shift and its application in cell imaging. (25th May 2021)

• Record Type: Journal Article
• Authors: Zhang, Zhi-Hao; Li, Shaoqing; Yan, Yizhe; Qu, Jianbo; Wang, Jian-Yong
• Is Part Of: New journal of chemistry. Volume 45:Number 22(2021)
• Page Start: 9756
• Page End: 9760
• Publication Date: 2021-05-25
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/d1nj01319j
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : A novel fast-responsive fluorescent probe TzAr-H2 S based on 1, 3, 5-triazine was constructed to monitor endogenous H2 S. The probe TzAr-H2 S can quickly (only 20 s) detect H2 S with good selectivity, large Stokes shift (100 nm) and low cytotoxicity. Abstract : A novel fast-responsive fluorescent probe TzAr-H2S was constructed to realize the imaging of endogenous H2 S in living cells. This turn-on fluorescent probe TzAr-H2S can quickly (only 20 s) detect H2 S with good selectivity, large Stokes shift (100 nm) and low cytotoxicity, which might provide a powerful tool for understanding the regulation mechanism of hydrogen sulfide in cells.