Native valve infective endocarditis due to sequence type 97 community-associated methicillin-resistant Staphylococcus aureus complicated by meningitis and multiple septic emboli in a young healthy adult. Issue 6 (June 2022)

• Record Type: Journal Article
• Authors: Kawabe, Yuka; Sakurai, Aki; Sasaki, Toshiharu; Hasegawa, Makoto; Suzuki, Masahiro; Hoshino, Naoki; Nakashima, Chihiro; Maekawa, Atsuo; Doi, Yohei
• Is Part Of: Journal of infection and chemotherapy. Volume 28:Issue 6(2022)
• Page Start: 828
• Page End: 832
• Publication Date: 2022-06
• Subjects: Methicillin-resistant Staphylococcus aureus -- Community acquired infection -- Infective endocarditis; Chemotherapy -- Periodicals; Infection -- Periodicals; Communicable diseases -- Chemotherapy -- Periodicals; 615.5805
• DOI: 10.1016/j.jiac.2022.01.020
• Languages: English
• ISSNs: 1341-321X

Abstract

Abstract: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) can cause a wide variety of infections, ranging from skin and soft tissue infections to life-threatening invasive diseases such as necrotizing pneumonia and infective endocarditis. Here, we present a case of a healthy young female presenting with fever, headache and nausea, who was diagnosed with mitral valve infective endocarditis due to CA-MRSA and whose course was complicated by meningitis and multiple septic emboli. The causative MRSA strain belonged to sequence type 97 and harbored SCC mec Ⅳc but not lukS/F-PV genes. ST97, which is frequently isolated from livestock animals and known as a common lineage of livestock-associated MRSA, may cause invasive infection in the community.