Systematic comparison between BNT162b2 and CoronaVac in the seroprotection against SARS-CoV-2 Alpha, Beta, Gamma, and Delta variants. Issue 5 (May 2022)

• Record Type: Journal Article
• Authors: Au, Wing Ying; Ye, Chengjin; Briner, Sydney Leigh; Suarez, Gianmarco Domenico; Han, Jeewon; Xu, Xinzhou; Park, Jun-Gyu; Brindley, Melinda Ann; Martinez-Sobrido, Luis; Cheung, Peter Pak-Hang
• Is Part Of: Journal of infection. Volume 84:Issue 5(2022)
• Page Start: e55
• Page End: e57
• Publication Date: 2022-05
• Subjects: Infection -- Periodicals; Bacterial Infections -- Periodicals; Communicable Diseases -- Periodicals; Electronic journals; 616.905
• DOI: 10.1016/j.jinf.2022.02.030
• Languages: English
• ISSNs: 0163-4453

Abstract

Highlights: Sera from BNT162b2 recipients seroprotects more than Coronavac. While BNT162b2 seroprotect Beta less, Coronavac protects against all variants similarly to original WA1 strain. Antibodies elicited by Cornavac can bind to both Spike and Nucleocapsid, whereas BNT162b2 could only bind to spike.