Effects of Early Life Adversity on Pubertal Timing and Tempo in Black and White Girls: The National Growth and Health Study. Issue 3 (24th April 2022)

• Record Type: Journal Article
• Authors: Hamlat, Elissa June; Laraia, Barbara; Bleil, Maria E.; Deardorff, Julianna; Tomiyama, A. Janet; Mujahid, Mahasin; Shields, Grant S.; Brownell, Kristy; Slavich, George M.; Epel, Elissa S.
• Is Part Of: Psychosomatic medicine. Volume 84:Issue 3(2022)
• Page Start: 297
• Page End: 305
• Publication Date: 2022-04-24
• Subjects: early life stress -- pubertal development -- puberty -- race -- STRAIN -- BMI = body mass index -- HPA = hypothalamic-pituitary-adrenal -- HPG = hypothalamic-pituitary-gonadal -- NGHS = National Heart, Lung, and Blood Institute Growth and Health Study -- STRAIN = Stress and Adversity Inventory; Medicine, Psychosomatic -- Periodicals; 616.0805
• DOI: 10.1097/PSY.0000000000001048
• Languages: English
• ISSNs: 0033-3174

Abstract

ABSTRACT: Objective: Although exposure to abuse in early life predicts earlier pubertal timing, especially for girls, it is unclear if this association generalizes to nonabuse stressors. In addition, the impact of race on the stress-maturation association remains unknown. To address these issues, we examined whether race moderates the effects of early adversity on pubertal timing and tempo using a longitudinal study design. Methods: In a cohort of 9- and 10-year-old Black and White girls, pubertal (areolar and pubic hair) maturation was assessed annually for 7 years. In adulthood, 368 participants (186 Black, 182 White) reported on abuse and nonabuse stressors they experienced from ages 0 to 12 years. Results: Early life abuse was associated with earlier pubertal timing, as indexed by younger age at menarche ( b = −0.22, p = .005, 95% confidence interval [CI] = −0.39 to −0.06) and greater pubic hair development ( b = 0.11, p = .003, 95% CI = 0.04 to 0.18), in addition to slower pubertal tempo, as indexed by slower rate of pubic hair ( b = −0.03, p < .001, 95% CI = −0.05 to −0.01) and areolar ( b = −0.02, p = .02, 95% CI = −0.03 to −0.003) development. These associations were not found for nonabuse adversity. Black girls with early life abuse had greater pubic hair development ( b = 0.23, p < .001, 95% CI = 0.12 to 0.35) and were slower in pubic hair tempo ( b = −0.07, p < .001, 95% CI = −0.09 to −0.04) than their White counterparts. Conclusions: Screening for early life abuse may help address health disparities related to earlier pubertal timing.