Feasibility of Constructing an Automatic Meniscus Injury Detection Model Based on Dual-Mode Magnetic Resonance Imaging (MRI) Radiomics of the Knee Joint. (29th March 2022)

• Record Type: Journal Article
• Authors: Wang, Yi; Li, Yuanzhe; Huang, Meiling; Lai, Qingquan; Huang, Jing; Chen, Jiayang
• Other Names: Tang Min Academic Editor.
• Is Part Of: Computational and mathematical methods in medicine. Volume 2022(2022)
• Publication Date: 2022-03-29
• Subjects: Medicine -- Computer simulation -- Periodicals; Medicine -- Mathematical models -- Periodicals; 610.11
• DOI: 10.1155/2022/2155132
• Languages: English
• ISSNs: 1748-670X

Abstract

Abstract : Objective. To explore the feasibility of automatically detecting the degree of meniscus injury by radiomics fusion of dual-mode magnetic resonance imaging (MRI) features of sagittal and coronal planes of the knee joint. Methods. This retrospective study included 164 arthroscopically confirmed meniscus injuries in 152 patients admitted to the Department of Orthopaedics of our hospital from July 2018 to March 2021. A total of 1316-dimensional radiomics signatures were extracted from single-mode sagittal and coronal plane images of menisci, respectively. Then, the sagittal and coronal plane features were fused to form a dual-mode joint feature group with a total of 2632-dimensional radiomics signatures. The minimum redundancy maximum relevance (mRMR) algorithm and the least absolute shrinkage and selection operator (LASSO) regression were used to select features and generate optimal radiomics signatures. The single-mode sagittal plane feature model (Model 1), single-mode coronal plane feature model (Model 2), and the combined sagittal and coronal plane feature model (Model 3) performance were tested by receiver operating characteristic (ROC) curves and Delong test. The calibration curve test was used to verify the reliability of radiomics signatures of the three models. Results. The average intra- and interobserver intraclass correlation coefficients (ICCs) of the most significant 8-dimensional radiomics signatures of Model 1 and Model 2 were 0.935 (range 0.832-0.998) and 0.928 (range 0.845-0.998), respectively. All the three models had good detection performance; Model 3 had the most significant performance (the areas under the curve (AUCs) of training, and validation sets were 0.947 and 0.923, respectively), which was superior to Model 1 (AUCs of training set and validation set were 0.889 and 0.876, respectively) and Model 2 (AUCs of training set and validation set were 0.831 and 0.851, respectively). The detection probability of training and validation sets in the three models was highly consistent with the actual clinical probability. Conclusions. It is feasible to establish a model for automatic detection of meniscus damage by means of radiomics. The detection performance of the dual-mode knee MRI model is better than that of any single-mode model, showing potent feature analysis ability and outstanding detection performance.