An Unprecedented FeMo6@Ce‐Uio‐66 Nanocomposite with Cascade Enzyme‐Mimic Activity as Colorimetric Sensing Platform. Issue 22 (19th March 2022)

• Record Type: Journal Article
• Authors: Tong, Zhibo; Sha, Jingquan; Liu, Dingzhou; Xu, Mingqi
• Is Part Of: Chemistry. Volume 28:Issue 22(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-03-19
• Subjects: cascade enzyme-mimic activity -- Ce-Uio-66 -- dopamine -- integrated nanozymes -- polyoxometalates; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.202104213
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: Introducing the idea of integrated design and cascade activity into nanozyme, the novel integrated nanozymes (INAzymes), FeMo6 @Ce‐Uio‐66 (FC‐66(n)), were designed and synthesized by encapsulating iron‐based polyoxometalates (FeMo6 ) into the ceria‐based metal–organic framework (Ce‐Uio‐66). Due to the oxygen‐driven reversible Ce 3+ /Ce 4+ couple sites, the "Fenton‐like" effect by iron centers, the "nanoscale proximity" effects by nanocages, and their synergistic effects, FC‐66(n) as INAzymes exhibit elegant cascade enzyme‐mimic activities (oxidase‐, peroxidase‐, and Fenton‐like activity), which realizes INAzyme activities based on polyoxometalates based metal–organic framework (POMOFs). By employing dopamine (DA) detection as a model reaction, a high‐efficient fluorescent "turning‐on‐enhanced" platform under near neutral conditions was established. Abstract : Novel integrated nanozymes (INAzymes), FeMo6 @Ce‐Uio‐66 (FC‐66(n)), are designed and synthesized by encapsulating iron‐based polyoxometalates into the ceria‐based metal–organic framework. Due to the oxygen‐driven reversible Ce 3+ /Ce 4+ couple sites, the "Fenton‐like" effect by iron centers, the "nanoscale proximity" effects by nanocages and their synergistic effects, FC‐66(n) as INAzymes exhibit elegant cascade enzyme‐mimic activities. Based on the excellent catalytic activity of the FC‐66(n), an efficient fluorescent "turning‐on‐enhanced" platform for dopamine (DA) detection under near neutral conditions was established.