Delayed Hypersensitivity Reaction to Titanium-coated Polypropylene Mesh in Breast Reconstruction. Issue 4 (14th April 2022)

• Record Type: Journal Article
• Authors: Jouve, Eva; Giordano-Labadie, Françoise; Selmes, Gabrielle; Soule-Tholy, Marc; Navarro, Anne-Sophie; Gangloff, Dimitri; Meresse, Thomas; Duprez-Paumier, Raphaelle; Tournier, Emilie; Vaysse, Charlotte
• Is Part Of: Plastic and reconstructive surgery. Volume 10:Issue 4(2022)
• Page Start: e4232
• Publication Date: 2022-04-14
• Subjects: Surgery, Plastic -- Periodicals; Surgery, Plastic -- Periodicals; Reconstructive Surgical Procedures -- Periodicals; 617.95205
• DOI: 10.1097/GOX.0000000000004232
• Languages: English
• ISSNs: 2169-7574

Abstract

Abstract : Summary: Breast implant reconstructions increasingly incorporate meshes like the synthetic nonresorbable titanium-coated polypropylene mesh commercialized as Tiloop (Pfm medical). We report the case of a 48-year-old woman, with a medical history of nickel allergy, who presented with an extensive erythematous eruption, a periprosthetic reaction, and an axillary node reaction, 18 months after a unilateral prophylactic mastectomy. We excluded infectious, sarcoidosis and carcinomatosis. The patient's medical history, the clinical evolution, and the particularly fast and complete healing after removal of the mesh were suggestive of an unusual allergic reaction to the titanium in the titanium-coated polypropylene mesh. Titanium allergies are very rare events, predominantly described in the dental and orthopedic fields. We also discussed the hypothesis of a tardive red breast syndrome related to a synthetic mesh, also mediated by immunological response as described recently in another case report.