Intrathecal daptomycin use in a challenging case of Enterococcus faecium ventriculitis. Issue 4 (8th April 2022)

• Record Type: Journal Article
• Authors: Dhariwal, Ankush; Leff, Rachel; Allen, Mike; Cherian, Benny
• Is Part Of: Access microbiology. Volume 4:Issue 4(2022)
• Publication Date: 2022-04-08
• Subjects: daptomycin -- ventriculitis -- Enterococcus faecium -- VRE -- intrathecal -- external ventricular drain; Microbiology -- Periodicals; 579
• DOI: 10.1099/acmi.0.000230
• Languages: English
• ISSNs: 2516-8290

Abstract

Abstract : Treatment of ventriculitis caused by enterococci can be challenging, and antibiotic options are limited. We describe a case of device-related ventriculitis caused by vancomycin-resistant Enterococcus faecium, refractory to initial antibiotics. Our management approach included intrathecal daptomycin. There were no attributable adverse events, and the patient remained infection-free following ventriculo-peritoneal shunt insertion and cessation of antibiotics.