Sterile endophthalmitis after intravitreal triamcinolone acetonide injection: A case report series. (April 2022)

• Record Type: Journal Article
• Authors: Mahjoub, Ahmed; Ben Abdesslem, Nadia; Ben Abderrazek, Atf; Zaafrane, Nesrine; Mahjoub, Anis; Aoun, Hichem; Jabri, Ahmed; Krifa, Fethi; Ghorbel, Mohamed; Mahjoub, Hachemi
• Is Part Of: Annals of medicine and surgery. Volume 76(2022)
• Publication Date: 2022-04
• Subjects: Case report series -- Intravitreal injection -- Triamcinolone acetonide -- Sterile endophthalmitis; TA Triamcinolone acetonide -- IVTA Intra vitreal triamcinolone acetonide -- BCVA Best corrected visual acuity -- IOP Intraocular pressure -- OCT Optical coherence tomography; Surgery -- Periodicals; Medicine -- Periodicals; General Surgery -- Periodicals; Education, Medical -- Periodicals; Periodicals; 617
• DOI: 10.1016/j.amsu.2022.103537
• Languages: English
• ISSNs: 2049-0801

Abstract

Abstract: Corticosteroids have proven their effectiveness in the treatment of cystoid macular edema. Especially after an intravitreal injection. Triamcinolone acetonide is the most commonly used in the treatment of macular edema. Noninfectious endophthalmitis is a form of endophthalmitis that can occur in the absence of a defined germ after an intravitreal injection of triamcinolone acetonide. We report here the case of three diabetic patients, who presented with visual blur, three days after an intra vitreal triamcinolone acetonide injection performed in the right eye. The vitreous inflammation resolved spontaneously in the first two cases after three weeks, and after four weeks for the third. The diagnosis of sterile endophthalmitis was made in view of the spontaneous resolution of the inflammation without the use of intravitreal injection of antibiotics and/or vitreoretinal surgery. Highlights: Describe the development of sterile endophthalmitis after an intravitreal injection of triamcinolone acetonide in diabetic patients with macular edema. Enhance the differences between infections endophthalmitis and sterile endophthalmitis. Report our ophthalmology team's management in front of a sterile endophthalmitis in comparison to literature.