Frontispiece: Properties of the Reactants and Their Interactions within and with the Enzyme Binding Cavity Determine Reaction Selectivities. The Case of Fe(II)/2‐Oxoglutarate Dependent Enzymes. Issue 18 (28th March 2022)

Record Type:: Journal Article
Title:: Frontispiece: Properties of the Reactants and Their Interactions within and with the Enzyme Binding Cavity Determine Reaction Selectivities. The Case of Fe(II)/2‐Oxoglutarate Dependent Enzymes. Issue 18 (28th March 2022)
Main Title:: Frontispiece: Properties of the Reactants and Their Interactions within and with the Enzyme Binding Cavity Determine Reaction Selectivities. The Case of Fe(II)/2‐Oxoglutarate Dependent Enzymes
Authors:: Wojdyla, Zuzanna
Borowski, Tomasz
Abstract:: Abstract : The binding cavities of ODDs fine‐tune the selectivities of catalysed reactions by precise positioning of the substrate with respect to the iron cofactor and by specific cavity‐substrate interactions. The latter may outweigh the steric effects and the inherent reaction propensity of the reactants and thus settle product selectivity. For more information, see the Review by Z. Wojdyla and T. Borowski (DOI: 10.1002/chem.202104106 ).
Is Part Of:: Chemistry. Volume 28:Issue 18(2022)
Journal:: Chemistry
Issue:: Volume 28:Issue 18(2022)
Issue Display:: Volume 28, Issue 18 (2022)
Year:: 2022
Volume:: 28
Issue:: 18
Issue Sort Value:: 2022-0028-0018-0000
Page Start:: n/a
Page End:: n/a
Publication Date:: 2022-03-28
Subjects:: 2-oxoglutarate -- Fe(II) -- reaction mechanism -- regioselectivity -- selectivity
Chemistry -- Periodicals
540
Journal URLs:: http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3765 ↗
http://onlinelibrary.wiley.com/ ↗
DOI:: 10.1002/chem.202281863 ↗
Languages:: English
ISSNs:: 0947-6539
Deposit Type:: Legaldeposit
View Content:: Available online (eLD content is only available in our Reading Rooms) ↗
Physical Locations:: British Library DSC - 3168.860500
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Ingest File:: 21225.xml