The next major emergent infectious disease: reflections on vaccine emergency development strategies. (3rd April 2022)

• Record Type: Journal Article
• Authors: Bai, Yu; Wang, Qian; Liu, Mingchen; Bian, Lianlian; Liu, Jianyang; Gao, Fan; Mao, Qunying; Wang, Zhongfang; Wu, Xing; Xu, Miao; Liang, Zhenglun
• Is Part Of: Expert review of vaccines. Volume 21:Number 4(2022)
• Page Start: 471
• Page End: 481
• Publication Date: 2022-04-03
• Subjects: Major emergent infectious disease -- vaccine -- emergent development strategies -- reflections; Vaccines -- Periodicals; Vaccination -- Periodicals; 615.37205
• DOI: 10.1080/14760584.2022.2027240
• Languages: English
• ISSNs: 1476-0584

Abstract

ABSTRACT: Introduction: Major emergent infectious diseases (MEID) pose the most serious threat to human health. The research proposes targeted response strategies for the prevention and control of potential MEID. Areas covered: Based on the analysis of infectious diseases, this research analyzes pandemics that have a high probability of occurrence and aims to synthesize the past experience and lessons learned of controlling infectious diseases such as coronavirus, influenza, Ebola, etc. In addition, by integrating major infectious disease response guidelines developed by WHO, the European Union, the United States, and the United Kingdom, we intend to bring forward national vaccine R&D development strategies for emergency use. Expert opinion: We advise to establish and improve existing laws, regulations, and also prevention and control systems for the emergent R&D and application of vaccines in response to potential infectious diseases. The strategies would not only help increase the various abilities in response to the research, development, evaluation, production, and supervision of emergency vaccines, but also establish surrogate endpoint of immunogenicity protection in early clinical studies to enable a rapid evaluation of the efficacy of emergency vaccines.