Multipoint Costriking Nanodevice Eliminates Primary Tumor Cells and Associated‐Circulating Tumor Cells for Enhancing Metastasis Inhibition and Therapeutic Effect on HCC (Adv. Sci. 9/2022). Issue 9 (25th March 2022)

• Record Type: Journal Article
• Authors: Mu, Weiwei; Chu, Qihui; Yang, Huizhen; Guan, Li; Fu, Shunli; Gao, Tong; Sang, Xiao; Zhang, Zipeng; Liang, Shuang; Liu, Yongjun; Zhang, Na
• Is Part Of: Advanced science. Volume 9:Issue 9(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-03-25
• Subjects: Science -- Periodicals; 505
• DOI: 10.1002/advs.202270052
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : Metastasis Prevention In article number 2101472 by Yongjun Liu, Na Zhang, and co‐workers, a "roots and seeds" multipoint costriking strategy is proposed to eliminate primary tumors and associated‐circulating tumor cells (CTCs). The multipoint costriking nanodevice could specifically capture CTCs, dissociate CTC clusters, block the formation of CTC‐neutrophil clusters, and finally kill CTCs and primary tumor cells to prevent metastasis and enhance the therapeutic effect on hepatocellular carcinoma.