Ruthenaelectro-catalyzed C–H acyloxylation for late-stage tyrosine and oligopeptide diversification. Issue 12 (7th March 2022)

• Record Type: Journal Article
• Authors: Hou, Xiaoyan; Kaplaneris, Nikolaos; Yuan, Binbin; Frey, Johanna; Ohyama, Tsuyoshi; Messinis, Antonis M.; Ackermann, Lutz
• Is Part Of: Chemical science. Volume 13:Issue 12(2022)
• Page Start: 3461
• Page End: 3467
• Publication Date: 2022-03-07
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d1sc07267f
• Languages: English
• ISSNs: 2041-6520

Abstract

Abstract : Ruthenaelectro(ii /iv )-catalyzed intermolecular C–H acyloxylations of oligopeptides have been developed by the guidance of key experimental, CV and computational insights. Abstract : Ruthenaelectro(ii /iv )-catalyzed intermolecular C–H acyloxylations of phenols have been developed by guidance of experimental, CV and computational insights. The use of electricity bypassed the need for stoichiometric chemical oxidants. The sustainable electrocatalysis strategy was characterized by ample scope, and its unique robustness enabled the late-stage C–H diversification of tyrosine-derived peptides.