Hydrothermal water enabling one-pot transformation of amines to alcohols via supported Pd catalysts. Issue 4 (2nd March 2022)

• Record Type: Journal Article
• Authors: Wu, Lanxin; Yang, Yang; Cheng, Jiong; Wang, Xiaoguang; Huang, Qing; Jin, Fangming
• Is Part Of: Reaction chemistry & engineering. Volume 7:Issue 4(2022)
• Page Start: 839
• Page End: 843
• Publication Date: 2022-03-02
• Subjects: Reaction mechanisms (Chemistry) -- Periodicals; Chemical engineering -- Periodicals; Chemical engineering; Reaction mechanisms (Chemistry); Periodicals; 547.705
• DOI: 10.1039/d1re00578b
• Languages: English
• ISSNs: 2058-9883

Abstract

Abstract : One-pot transformation of amines into alcohols was achieved by exploiting the unique characteristics of hydrothermal water, surpassing previous methods which require multiple approaches or complex catalysts. Abstract : Simple, direct conversion of amines to alcohols is quite rare and remains challenging. Here, with the unique catalytic role of hydrothermal water, two green and one-pot strategies were proposed to enable water nucleophilic attack at amines, which were achieved by dehydrogenation of amines or building a targeting group. Furthermore, one strategy was applied in the conversion of glutamic acid, the most abundant amino acid in microalgae, to γ-butyrolactone, which is an industrial chemical derived from fossil fuels. This study provides simple and new methods for the deamination of amines and could provide to new insight into the utilization of protein-rich biomass.