2, 7-Diazapyrenes: a brief review on synthetic strategies and application opportunities. Issue 15 (24th March 2022)

• Record Type: Journal Article
• Authors: Mukherjee, Anindita; Akulov, Alexey A.; Santra, Sougata; Varaksin, Mikhail V.; Kim, Grigory A.; Kopchuk, Dmitry S.; Taniya, Olga S.; Zyryanov, Grigory V.; Chupakhin, Oleg. N.
• Is Part Of: RSC advances. Volume 12:Issue 15(2022)
• Page Start: 9323
• Page End: 9341
• Publication Date: 2022-03-24
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d2ra00260d
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : This review discusses the synthetic routes for 2, 7-diazapyrene derivatives and highlights the opportunities for application of 2, 7-diazapyrenes, including their remarkable photophysical and supramolecular properties, in sensors and related areas. Abstract : 2, 7-Diazapyrenes are promising azaaromatic scaffolds with a unique structural geometry and supramolecular properties. This core moiety and its derivatives with some N -methyl cations like N -methyl-2, 7, -diazapyrenium, and N, N ′-dimethyl-2, 7-diazapyrenium attract special attention due to their challenging photophysical properties, especially in the context of interactions with DNA and some of its mononucleotides. This review focuses on the analysis of the main synthetic approaches to 2, 7-diazapyrene and its functional derivatives employing various strategies under different reaction conditions. The opportunities of applications of 2, 7-diazapyrenes, including their remarkable photophysical and supramolecular properties, DNA-bindings, in sensors, molecular electronics, supramolecular systems, and related areas are also highlighted.