Fecal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) RNA Is Associated With Decreased Coronavirus Disease 2019 (COVID-19) Survival. (10th July 2021)

• Record Type: Journal Article
• Authors: Das Adhikari, Upasana; Eng, George; Farcasanu, Mara; Avena, Laura E; Choudhary, Manish C; Triant, Virginia A; Flagg, Meaghan; Schiff, Abigail E; Gomez, Isabella; Froehle, Leah M; Diefenbach, Thomas J; Ronsard, Larance; Lingwood, Daniel; Lee, Grace C; Rabi, Seyed Alireza; Erstad, Derek; Velmahos, George; Li, Jonathan Z; Hodin, Richard; Stone, James R; Honko, Anna N; Griffiths, Anthony; Yilmaz, Ömer H; Kwon, Douglas S
• Is Part Of: Clinical infectious diseases. Volume 74:Number 6(2022)
• Page Start: 1081
• Page End: 1084
• Publication Date: 2021-07-10
• Subjects: SARS CoV-2 -- mortality -- fecal -- RNA -- organoids -- GI epithelium -- phylogenetics; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciab623
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: The clinical significance of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) RNA in stool remains uncertain. We found that extrapulmonary dissemination of infection to the gastrointestinal tract, assessed by the presence of SARS-CoV-2 RNA in stool, is associated with decreased coronavirus disease 2019 (COVID-19) survival. Measurement of SARS-CoV-2 RNA in stool may have utility for clinical risk assessment.