Conjugation of RNA via 2′-OH acylation: Mechanisms determining nucleotide reactivity. Issue 22 (28th February 2022)
- Record Type:
- Journal Article
- Title:
- Conjugation of RNA via 2′-OH acylation: Mechanisms determining nucleotide reactivity. Issue 22 (28th February 2022)
- Main Title:
- Conjugation of RNA via 2′-OH acylation: Mechanisms determining nucleotide reactivity
- Authors:
- Jash, Biswarup
Kool, Eric T. - Abstract:
- Abstract : Kinetics experiments reveal the importance of steric and inductive effects in RNA acylation. Abstract : The acylation reactivity of RNA 2′-OH groups has proven broadly useful for labeling and mapping RNA. Here we perform kinetics studies to test the mechanisms governing this reaction, and we find strong steric and inductive effects modulating reactivity. The results shed light on new strategies for improved conjugation and mapping.
- Is Part Of:
- Chemical communications. Volume 58:Issue 22(2022)
- Journal:
- Chemical communications
- Issue:
- Volume 58:Issue 22(2022)
- Issue Display:
- Volume 58, Issue 22 (2022)
- Year:
- 2022
- Volume:
- 58
- Issue:
- 22
- Issue Sort Value:
- 2022-0058-0022-0000
- Page Start:
- 3693
- Page End:
- 3696
- Publication Date:
- 2022-02-28
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d2cc00660j ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 21206.xml