Electrochemical synthesis of dipyrazolo/dipyrimidine-fused pyridines via oxidative domino cyclization of C(sp3)–H bonds. Issue 6 (11th February 2022)

• Record Type: Journal Article
• Authors: Qian, Peng; Xu, Linna; Wang, Wenyan; Zhang, Lin; Tang, Liang; Liu, Jiaojiao; Sheng, Liangquan
• Is Part Of: Organic chemistry frontiers. Volume 9:Issue 6(2022)
• Page Start: 1662
• Page End: 1667
• Publication Date: 2022-02-11
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d1qo01641e
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : An electrochemically oxidative domino cyclization reaction of methyl azaarenes/ketones with pyrazol-5-amines and 6-amino-pyrimidine-2, 4-diones was developed, providing a variety of dipyrazolo/dipyrimidine-fused pyridines with moderate to good yields. Abstract : An electrochemically oxidative domino cyclization reaction of methyl azaarenes/ketones with pyrazol-5-amines and 6-amino-pyrimidine-2, 4-diones was developed, providing a variety of dipyrazolo[3, 4- b :4′, 3′- e ]pyridines and dipyrimidine-fused pyridines with moderate to good yields. The reaction involved two C–C bond formations and one C–N bond formation in one pot. Moreover, the photoluminescence properties of the representative dipyrazolo[3, 4- b :4′, 3′- e ]pyridines were investigated.