Recyclable and reusable ionic liquid-supported azo precursors in Mitsunobu reactions. Issue 11 (1st March 2022)

• Record Type: Journal Article
• Authors: Lin, Cheng-Kun; Lee, Wei; Wu, Chun-Fu; Shih, Fang-Yi
• Is Part Of: Organic & biomolecular chemistry. Volume 20:Issue 11(2022)
• Page Start: 2217
• Page End: 2221
• Publication Date: 2022-03-01
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d2ob00039c
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : The presented work describes the first combination of a new and stable form of ionic liquid supported azo precursors and a terminal oxidant that show high reactivity toward Mitsunobu reactions. Abstract : A new type of azo precursor, ionic liquid-supported hydrazidecarboxylate, was synthesized and applied in Mitsunobu reactions. The developed reagent is recyclable during the reaction and reusable after recovery by the ionic liquids. The ionic liquid-based azo precursor in conjugation with PhI(OAc)2 has been proved to be useful in the formation of carbon–oxygen, carbon–nitrogen, and carbon–sulfur bonds.