A Nanocoating Co‐Localizing Nitric Oxide and Growth Factor onto Individual Endothelial Cells Reveals Synergistic Effects on Angiogenesis (Adv. Healthcare Mater. 6/2022). Issue 6 (16th March 2022)

• Record Type: Journal Article
• Authors: Jeong, Hyejoong; Choi, Daheui; Oh, Yoogyeong; Heo, Jiwoong; Hong, Jinkee
• Is Part Of: Advanced healthcare materials. Volume 11:Issue 6(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-03-16
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.202270029
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : Angiogenesis In article number 2102095 by Jinkee Hong and co‐workers, a nanocoating, co‐localizing nitric oxide and vascular endothelial growth factor (VEGF), is successfully formed on a surface of endothelial cells, harnessing biocompatible polymers via a layer‐by‐layer assembly technique. The nanocoating efficiently delivers labile nitric oxide to cells and induces a synergistic effect with VEGF to naturally enhance angiogenesis signals and subsequent vascularization, which can be utilized for stem cell transplantation for vascular regeneration.