A novel NiVP/Pi-based flexible sensor for direct electrochemical ultrasensitive detection of cholesterol. Issue 16 (3rd February 2022)

• Record Type: Journal Article
• Authors: Thakur, Neha; Mandal, Debaprasad; Nagaiah, Tharamani C.
• Is Part Of: Chemical communications. Volume 58:Issue 16(2022)
• Page Start: 2706
• Page End: 2709
• Publication Date: 2022-02-03
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d1cc07115g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A novel non-enzymatic electrochemical sensor was constructed to achieve a highly selective and ultrasensitive detection of cholesterol and in this way address the problems related to serious coronary heart disease. Abstract : A novel non-enzymatic electrochemical sensor was constructed to achieve a highly selective and ultrasensitive detection of cholesterol to address the problems related to serious coronary heart disease. The NiVP/Pi-based sensor exhibited ultra-high sensitivity of 5510.18 μA μM −1 cm −2 and 36.8 μA μM −1 cm −2 for 1 nM to 10 μM and 100 μM to 10 mM of cholesterol, respectively, with an ultra-low detection limit of 1 aM, along with superior selectivity for cholesterol when exposed to various interferents such as ascorbic acid, glucose and uric acid. Also, a novel NiVP/Pi-based flexible sensor coated onto Whatman filter paper was developed and displayed superior sensitivity, even with a human blood serum sample at physiological pH.