Harnessing intercellular signals to engineer the soil microbiome. Issue 2 (1st December 2021)

• Record Type: Journal Article
• Authors: Connolly, Jack A.; Harcombe, William R.; Smanski, Michael J.; Kinkel, Linda L.; Takano, Eriko; Breitling, Rainer
• Is Part Of: Natural product reports. Volume 39:Issue 2(2022)
• Page Start: 311
• Page End: 324
• Publication Date: 2021-12-01
• Subjects: Natural products -- Periodicals; Produits naturels -- Périodiques; 547.7
• DOI: 10.1039/d1np00034a
• Languages: English
• ISSNs: 0265-0568

Abstract

Abstract : This review covers intercellular signalling in the soil microbiome and its importance in regulating key beneficial functions. We consider the possibilities for how we can engineer soil microbiome signalling to unlock tangible benefits to crops. Abstract : Covering: Focus on 2015 to 2020 Plant and soil microbiomes consist of diverse communities of organisms from across kingdoms and can profoundly affect plant growth and health. Natural product-based intercellular signals govern important interactions between microbiome members that ultimately regulate their beneficial or harmful impacts on the plant. Exploiting these evolved signalling circuits to engineer microbiomes towards beneficial interactions with crops is an attractive goal. There are few reports thus far of engineering the intercellular signalling of microbiomes, but this article argues that it represents a tremendous opportunity for advancing the field of microbiome engineering. This could be achieved through the selection of synergistic consortia in combination with genetic engineering of signal pathways to realise an optimised microbiome.