Cancer disparities among non‐Hispanic urban American Indian and Alaska Native populations in the United States, 1999‐2017. Issue 8 (4th February 2022)

• Record Type: Journal Article
• Authors: Melkonian, Stephanie C.; Jim, Melissa A.; Pete, Dornell; Poel, Amy; Dominguez, Adrian E.; Echo‐Hawk, Abigail; Zhang, Stephanie; Wilson, Reda J.; Haverkamp, Donald; Petras, Lindsey; Pohlenz, Ashley
• Is Part Of: Cancer. Volume 128:Issue 8(2022)
• Page Start: 1626
• Page End: 1636
• Publication Date: 2022-02-04
• Subjects: Alaska Native -- American Indian -- cancer incidence -- health disparity -- trends -- urban; Cancer -- Periodicals; Cancer -- Cytopathology -- Periodicals; 616.99405
• DOI: 10.1002/cncr.34122
• Languages: English
• ISSNs: 0008-543X

Abstract

Abstract : Background: Disparities in cancer incidence have not been described for urban American Indian/Alaska Native (AI/AN) populations. The purpose of the present study was to examine incidence rates (2008‐2017) and trends (1999‐2017) for leading cancers in urban non‐Hispanic AI/AN (NH AI/AN) compared to non‐Hispanic White (NHW) populations living in the same urban areas. Methods: Incident cases from population‐based cancer registries were linked with the Indian Health Service patient registration database for improved racial classification of NH AI/AN populations. This study was limited to counties in Urban Indian Health Organization service areas. Analyses were conducted by geographic region. Age‐adjusted rates (per 100, 000) and trends (joinpoint regression) were calculated for leading cancers. Results: Rates of colorectal, liver, and kidney cancers were higher overall for urban NH AI/AN compared to urban NHW populations. By region, rates of these cancers were 10% to nearly 4 times higher in NH AI/AN compared to NHW populations. Rates for breast, prostate, and lung cancer were lower in urban NH AI/AN compared to urban NHW populations. Incidence rates for kidney, liver, pancreatic, and breast cancers increased from 2% to nearly 7% annually between 1999 to 2017 in urban NH AI/AN populations. Conclusions: This study presents cancer incidence rates and trends for the leading cancers among urban NH AI/AN compared to urban NHW populations for the first time, by region, in the United States. Elevated risk of certain cancers among urban NH AI/AN populations and widening cancer disparities highlight important health inequities and missed opportunities for cancer prevention in this population. Abstract : This study presents cancer incidence rates and trends for the leading cancers among urban non‐Hispanic American Indian and Alaska Native (NH AI/AN) populations compared to urban non‐Hispanic White populations for the first time, by region, in the United States. Elevated risk of certain cancers among urban NH AI/AN populations and widening cancer disparities highlight important health inequities and missed opportunities for cancer prevention in this population.