Trichocladabiflavone A, a chalcone-flavonone type biflavonoid from Selaginella trichoclada Alsto. Issue 7 (3rd April 2022)

• Record Type: Journal Article
• Authors: Xie, Yang; Yao, Xiao-Chang; Tan, Lei-Hong; Long, Hong-Ping; Xu, Ping-Sheng; Li, Jing; Tan, Gui-Shan
• Is Part Of: Natural product research. Volume 36:Issue 7(2022)
• Page Start: 1797
• Page End: 1802
• Publication Date: 2022-04-03
• Subjects: Selaginella trichoclada -- biflavonoids -- trichocladabiflavone A -- chalcone-flavonone; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2020.1817920
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A chalcone-flavonone type biflavonoid, trichocladabiflavone A (1 ), along with eight known biflavonoids (2–9 ) were isolated from the 70% EtOH extract of Selaginella trichoclada . Their structures were elucidated by extensive spectroscopic analyses. Compound 1 was the first chalcone-flavonone type biflavonoid reported in the genus Selaginella . Moreover, compound 1 exhibited moderate cytotoxicity against DU145, MCF-7 and PC3 human cancer cell lines. Graphical Abstract: