Parmosidone K, a new meta-depsidone from the lichen Parmotrema tsavoense. Issue 8 (18th April 2022)

• Record Type: Journal Article
• Authors: Nguyen, Thi-Hoai-Thu; Nguyen, Thi-My-Nhung; Nguyen, Thanh-Trung; Nguyen, Huu-Hung; Nguyen, Ngoc-Hong; Mai, Dinh-Tri; Huynh, Bui-Linh-Chi; Tran, Cong-Luan; Duong, Thuc-Huy
• Is Part Of: Natural product research. Volume 36:Issue 8(2022)
• Page Start: 2037
• Page End: 2042
• Publication Date: 2022-04-18
• Subjects: Parmotrema -- Parmotrema tsavoense -- depsidone -- parmosidone -- α-glucosidase; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2020.1844697
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Further phytochemical investigation on P. tsavoense led to one new meta -depsidone, parmosidone K together with one known compound, barbatic acid. Their structures were determined by 1D and 2D NMR analysis, high resolution mass spectroscopy, and comparison their NMR data with those reported in literatures. Parmosidone K was evaluated for α-glucosidase inhibition and revealed the powerful activity with IC50 value of 3.12 µM. Graphical Abstract: