Torque teno sus virus 1 (TTSuV1) and 2 (TTSuV2) viral loads in serum of postweaning multisystemic wasting syndrome (PMWS)-affected and healthy pigs in Brazil. (August 2015)

• Record Type: Journal Article
• Authors: Teixeira, Thais Fumaco; Cibulski, Samuel Paulo; dos Santos, Helton Fernandes; Wendlant, Adriéli; de Sales Lima, Francisco Esmaile; Schmidt, Candice; Franco, Ana Cláudia; Roehe, Paulo Michel
• Is Part Of: Research in veterinary science. Volume 101(2015)
• Page Start: 38
• Page End: 41
• Publication Date: 2015-08
• Subjects: Torque teno sus virus (TTSuV) -- Anellovirus -- Postweaning multisystemic wasting syndrome (PMWS) -- Quantitative PCR (qPCR); Veterinary medicine -- Periodicals; Veterinary Medicine -- Periodicals; Médecine vétérinaire -- Périodiques; Médecine vétérinaire -- Recherche -- Périodiques; Diergeneeskunde; 636.089
• DOI: 10.1016/j.rvsc.2015.05.016
• Languages: English
• ISSNs: 0034-5288

Abstract

Abstract: Associations between Torque teno sus viruses (TTSuVs) and the occurrence of postweaning multisystemic wasting syndrome (PMWS) have been reported with controversial results. Currently, no studies have been performed comparing simultaneously viral loads of TTSuVs and PCV2. To examine the role for TTSuVs in PMWS-affected animals, a SYBR Green-based quantitative PCR (qPCR) was designed to detect and quantify TTSuV1, TTSuV2 and PCV2 genomes in swine sera. TTSuV1 genome loads were significantly higher in healthy adults than in young and SPF animals (p < 0.05) suggesting that the prevalence of TTSuV1 infection increases with age and bears no association with PMWS. Regarding TTSuV2, no significant variation was detected in viral loads within any of the groups. As expected, PCV2 genome loads were higher in PMWS-affected swine than in healthy or SPF animals (p < 0.001). These findings provide clear evidence to indicate that neither TTSuV1 nor TTSuV2 viral loads have any correlation with the occurrence of PMWS. Highlights: TTSuV1 and TTSuV2 viral loads are not correlated with PMWS. TTSuV1 loads were higher in healthy adults than in healthy young and SPF animals. These data indicate a wide distribution of TTSuV1 and TTSuV2 infections in swine.