COVID-19-positivity in a heart transplant recipient—antibody-mediated rejection or SARS-CoV-2-associated cardiac injury?. Issue 1 (24th January 2022)

• Record Type: Journal Article
• Authors: Hanson, Paul J; Liu-Fei, Felicia; Lai, Chi; Toma, Mustafa; McManus, Bruce M
• Is Part Of: Oxford medical case reports. Volume 2022:Issue 1(2022)
• Publication Date: 2022-01-24
• Subjects: Clinical medicine -- Case studies -- Periodicals; 616.09
• DOI: 10.1093/omcr/omab143
• Languages: English
• ISSNs: 2053-8855

Abstract

ABSTRACT: Through the ongoing and heightening coronavirus disease 2019 (COVID-19) pandemic, the heart has been implicated as a central target of injury associated with significantly increased morbidity and mortality. Correspondingly, heart transplant recipients are a vulnerable population for which insufficient research has been conducted. Pathologic antibody-mediated rejection (pAMR) of cardiac allografts shares many characteristics with COVID-19-associated cardiac injury. In this case study, we investigate a 57-year-old female who contracted COVID-19 11 days postheart transplant and was observed to have pAMR while positive for laboratory-confirmed COVID-19, resulting in a diagnostic conundrum.