Platelet rich fibrin: A novel treatment for trophic ulcer in Hansen's disease. (April 2022)

• Record Type: Journal Article
• Authors: Dorjay, Konchok; Tandon, Sidharth; Singh, Ajeet; Sharma, Satish; Sardana, Kabir
• Is Part Of: Tropical doctor. Volume 52:Number 2(2022)
• Page Start: 293
• Page End: 297
• Publication Date: 2022-04
• Subjects: Platelet rich fibrin -- Trophic ulcer -- Hansen's disease Apart from proper footwear for prevention -- one simple and elegant intervention involves the use of platelet rich fibrin; Tropical medicine -- Periodicals; Medical care -- Developing countries -- Periodicals; Developing Countries -- Periodicals; Tropical Medicine -- Periodicals; Tropische geneeskunde; 616.9883
• DOI: 10.1177/00494755211069440
• Languages: English
• ISSNs: 0049-4755

Abstract

Patients with Hansen's disease are liable to develop non-healing trophic ulcers. The aim of this study was to determine the efficacy of autologous platelet rich fibrin (PRF) applied at weekly intervals in the management of trophic ulcers. The mean age of the patients, duration and size of ulcer were 44.3 years, 7.4 months and 6.25cm 2 respectively. After the third sessions of weekly dressing, there was a significant reduction in the ulcer area (p value = 0.015). All ulcers healed by a maximum of six weeks. No adverse events were noted. PRF thus seems a feasible, safe, simple and cost-effective treatment method.