Urtica dioica-Derived Phytochemicals for Pharmacological and Therapeutic Applications. (24th February 2022)

• Record Type: Journal Article
• Authors: Taheri, Yasaman; Quispe, Cristina; Herrera-Bravo, Jesús; Sharifi-Rad, Javad; Ezzat, Shahira M.; Merghany, Rana M.; Shaheen, Shabnum; Azmi, Lubna; Prakash Mishra, Abhay; Sener, Bilge; Kılıç, Mehtap; Sen, Surjit; Acharya, Krishnendu; Nasiri, Azadeh; Cruz-Martins, Natália; Tsouh Fokou, Patrick Valere; Ydyrys, Alibek; Bassygarayev, Zhandos; Daştan, Sevgi Durna; Alshehri, Mohammed M.; Calina, Daniela; Cho, William C.
• Other Names: Mota da Silva Lu sa Academic Editor.
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2022(2022)
• Publication Date: 2022-02-24
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2022/4024331
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : Urtica dioica belongs to the Urticaceae family and is found in many countries around the world. This plant contains a broad range of phytochemicals, such as phenolic compounds, sterols, fatty acids, alkaloids, terpenoids, flavonoids, and lignans, that have been widely reported for their excellent pharmacological activities, including antiviral, antimicrobial, antihelmintic, anticancer, nephroprotective, hepatoprotective, cardioprotective, antiarthritis, antidiabetic, antiendometriosis, antioxidant, anti-inflammatory, and antiaging effects. In this regard, this review highlights fresh insight into the medicinal use, chemical composition, pharmacological properties, and safety profile of U. dioica to guide future works to thoroughly estimate their clinical value.