COVID-19-associated Isolated Cortical Vein Thrombosis: Detection of SARS‐CoV‐2 in CSF. (July 2022)

• Record Type: Journal Article
• Authors: Oktar, Ayla Çulha; Göçgün, Nurdan; Yaşgüçlükal, Miray Atacan; Bayar, Muhammet Duran; Alaçam, Sema; Karabulut, Nuran; Duman, Ezgi Bakırcıoğlu; Şişman, Büşra; Baştan, Birgül; Balcı, Belgin Petek; Çokar, Özlem
• Is Part Of: Neurohospitalist. Volume 12:Number 3(2022)
• Page Start: 520
• Page End: 523
• Publication Date: 2022-07
• Subjects: COVID-19 -- intracranial sinus thrombosis -- seizures; Nervous system -- Diseases -- Periodicals; Neurology -- Periodicals; 616.8
• DOI: 10.1177/19418744221079145
• Languages: English
• ISSNs: 1941-8744

Abstract

COVID-19 has been associated with central nervous system manifestations; however, cerebral venous thrombosis is rarely reported. A 34-year-old woman was admitted to the hospital with headache and recurrent seizures; she was recently discharged after COVID-19 pneumonia. Cranial magnetic resonance imaging and magnetic resonance venography showed cortical vein thrombosis in the right frontal lobe. SARS-CoV-2 RNA was detected in cerebrospinal fluid analysis. The patient was anticoagulated and put on antiepileptics. The most probable mechanism underlying the venous thrombosis is COVID-19-associated hypercoagulability. However, the relation between the viral RNA in cerebrospinal fluid analysis and the thrombosis is controversial.