New-onset lupus nephritis associated with COVID-19 infection. (July 2022)

• Record Type: Journal Article
• Authors: Kazzi, Brigitte; Fine, Derek; Geetha, Duvuru; Chung, Melody; Monroy-Trujillo, Manny; Timlin, Homa
• Is Part Of: Lupus. Volume 31:Number 8(2022)
• Page Start: 1007
• Page End: 1011
• Publication Date: 2022-07
• Subjects: systemic lupus erythematosus -- COVID-19 -- lupus nephritis; Systemic lupus erythematosus -- Periodicals; 616.772005
• DOI: 10.1177/09612033221098571
• Languages: English
• ISSNs: 0961-2033

Abstract

A dysregulated immune response plays a critical role in systemic lupus erythematosus (SLE) pathogenesis. Environmental factors such as viruses, including coronavirus 2 (COVID-19), have been described to play a role in SLE presentation and exacerbation. These viruses trigger a host's humoral and cellular immunities typically essential in elimination of the viral infection. We present a case of a Hispanic male who developed new-onset lupus nephritis class II after a COVID-19 infection.