Enantioselective chiral sorption of 1-phenylethanol by homochiral 1D coordination polymers. Issue 4 (13th January 2022)

• Record Type: Journal Article
• Authors: Cao, Winnie; Missen, Owen P.; Turner, David R.
• Is Part Of: Inorganic chemistry frontiers. Volume 9:Issue 4(2022)
• Page Start: 709
• Page End: 718
• Publication Date: 2022-01-13
• Subjects: Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/d1qi01457a
• Languages: English
• ISSNs: 2052-1553

Abstract

Abstract : Enantiomeric selectivity is shown within the pores of a 1D coordination polymer, dependent on the nature of the pore space. Abstract : Enantioselective resolution by coordination polymers has the potential to provide a high degree of discrimination by virtue of well-defined pores and the possibility of identifying and modifying binding sites. Differences in enantioselective behaviour of two closely-related chiral 1D coordination polymers are shown to relate to their slight differences in structure. The coordination polymers, 1 and 2, contain an enantiopure dicarboxylate diimide ligand (AlaPmDI 2− ) alongside an achiral co-ligand, 1, 4-bis(imidazol-1-yl-methyl)benzene (bix), with the substantiative difference between the two being replacement of one AlaPmDI 2− by two chloride ligands. Despite being one-dimensional, both present small channels of intrinsic chirality. Compound 1 was found to exhibit modest enantioselectivity for ( R )-1-phenylethanol (1-PE) from static sorption, while 2 did not show any enantioselectivity in its uptake, although still sorbed the guest. Single crystal data of 1-PE⊂1 indicates that the enantioselective preference is due to an array of interactions with the hydroxyl group of the ( R )-enantiomer. Use of 1 in a pseudo-LC micro-column is able to provide enantio-enriched samples from a dynamic separation.