Huffing and twist: Fatal Torsade de pointes associated with Tetrafluoroethane Inhalation and amphetamine use. Issue 8 (4th May 2021)

• Record Type: Journal Article
• Authors: Burke, Joseph; Haigney, Mark C. P.; Farasat, Morteza; Mehler, Philip S.; Krantz, Mori J.
• Is Part Of: Clinical case reports. Volume 9:Issue 8(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-05-04
• Subjects: hERG -- huffing -- Ikr -- sudden cardiac death -- torsade de pointes; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.3838
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: Many volatile chemicals inhaled for a recreational high have a chemical structure similar to chloroform and may lead to Ikr blockade and subsequent torsades de pointes. This is one potential mechanism of action for huffing‐associated sudden death. Abstract : Many volatile chemicals inhaled for a recreational high have a chemical structure similar to chloroform and may lead to Ikr blockade and subsequent torsades de pointes. This is one potential mechanism of action for huffing‐associated sudden death.