Hereditary Angioedema Post-liver Transplant. Issue 3 (5th August 2021)

• Record Type: Journal Article
• Authors: Al Rawahi, Yusriya; Wong, Melanie; Stormon, Michael
• Is Part Of: JPGN reports. Volume 2:Issue 3(2021)
• Page Start: e091
• Publication Date: 2021-08-05
• Subjects: cholestatic liver disease -- Hereditary angioedema -- inborn errors of metabolism; Pediatric gastroenterology -- Periodicals; Children -- Nutrition -- Periodicals; Children -- Nutrition; Pediatric gastroenterology; Infant Nutritional Physiological Phenomena; Child Nutritional Physiological Phenomena; Gastrointestinal Diseases; Infant; Child; Periodicals; Periodical; Case Reports; 618.9233
• DOI: 10.1097/PG9.0000000000000091
• Languages: English
• ISSNs: 2691-171X

Abstract

Abstract : Liver transplantation is the standard of care in managing different types of liver disorders as well as a variety of inborn errors of metabolism. In the latter scenario, the liver-based enzyme abnormality is corrected by transplantation. Although rare, liver transplantation may result in the transmission of an inborn error of metabolism to the recipient. The present report describes the development of acquired hereditary angioedema likely following liver transplantation, with notable improvement with the initiation of C1 esterase inhibitor replacement therapy. This case report describes another example of a hepatic synthesis defect that, although rare, but can be acquired from donor's livers.