Recent advances in catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes. Issue 1 (15th October 2021)

• Record Type: Journal Article
• Authors: Liu, Xiao-Lan; Jiang, Luo-Bin; Luo, Mu-Peng; Ren, Zhi; Wang, Shou-Guo
• Is Part Of: Organic chemistry frontiers. Volume 9:Issue 1(2022)
• Page Start: 265
• Page End: 280
• Publication Date: 2021-10-15
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d1qo01223a
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : Catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes represents one of the most straightforward and powerful protocols to construct diverse enantioenriched highly functionalized N-heteroarenes. Abstract : Catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes represents one of the most straightforward and powerful protocols to construct diverse enantioenriched highly functionalized N-heteroarene products. Efficient catalytic systems and a variety of strategies for highly chemo- and stereoselective C–H functionalization of electron-deficient N-containing heteroarenes have been developed over the past few decades. This review summarized the rapid progress in the catalytic asymmetric C–H functionalization of N-containing heteroarenes and discussed the challenges and potential of the field in the current stage.