Lower urinary tract symptoms are associated with clinically relevant depression, anxiety, and stress symptoms. (31st December 2022)

• Record Type: Journal Article
• Authors: Vartolomei, Liliana; Cotruș, Andrei; Tătaru, Sabin Octavian; Vartolomei, Mihai Dorin; Man, Adrian; Ferro, Matteo; Stanciu, Camelia; Sin, Anca Ileana; Shariat, Shahrokh F.
• Is Part Of: Aging male. Volume 25:Number 1(2022)
• Page Start: 62
• Page End: 66
• Publication Date: 2022-12-31
• Subjects: Depression -- anxiety -- stress -- testosterone deficiency -- lower urinary tract symptoms; Aging -- Periodicals; Men -- Periodicals; Gerontology -- Periodicals; Men -- Health and hygiene -- Periodicals; Aging -- periodicals; Geriatric -- periodicals; Men -- periodicals; Aged -- periodicals; Aged, 80 and over -- periodicals; 612.67
• DOI: 10.1080/13685538.2022.2040981
• Languages: English
• ISSNs: 1368-5538

Abstract

Abstract: Objectives: To investigate the correlation between lower urinary tract symptoms (LUTS), erectile dysfunction (ED), and testosterone deficiency (TD) with depressive, stress, and anxiety symptoms. Material and methods: From October 2019 to March 2020, 113 males were included. Inclusion criteria: age 40–75, no clinical suspicion of prostate cancer, no serious cardiovascular comorbidities. All patients completed a set of questionnaires: International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF-5), and Depression Anxiety Stress Scales (DASS-21). Results: Median age was 62 years (range 40–74), mean IPSS score was 10.94 (SD 7.75), mean IIEF-5 score 13.12 (SD 7.08), and mean DASS-21 score 11.35 (SD 8.24). According to DASS-21 subscales, 28 (24.8%) patients had depressive symptoms, 25 (22.1%) anxiety symptoms, and 25 (22.1%) stress symptoms. Depression was associated with LUTS (14.5 vs. 8 score, p = .002). Similarly, stress symptoms were associated with LUTS (IPSS 15 vs. 7 score, p = .0001) and with ED (IIEF-5 5 vs. 15 score, p = .01). Positive Spearman's rho correlations between LUTS and all three, depression, anxiety, and stress symptoms were found ( p values <.001). Conclusions: LUTS is associated with depression, anxiety, and stress symptoms. Screening for these symptoms could help with individual counseling and management.