Directing the H2-driven selective regeneration of NADH via Sn-doped Pt/SiO2. Issue 4 (3rd February 2022)

• Record Type: Journal Article
• Authors: Burnett, Joseph W. H.; Li, Jianwei; McCue, Alan J.; Kechagiopoulos, Panagiotis N.; Howe, Russell F.; Wang, Xiaodong
• Is Part Of: Green chemistry. Volume 24:Issue 4(2022)
• Page Start: 1451
• Page End: 1455
• Publication Date: 2022-02-03
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/d1gc04414a
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : High 1, 4-NADH selectivity (90% at full conversion) has been achieved in H2 -driven NAD + reduction using a PtSn/SiO2 bimetallic catalyst, offering a strategy for the development of heterogeneous catalysts for NADH regeneration. Abstract : H2 -Driven NADH regeneration has long suffered from low selectivity when non-enzymatic, particularly heterogeneous catalysts, are used. In addition to the unselective nature of the catalysts, the typically unmeasured NAD + conversion has inevitably hindered catalyst development. Here we report Sn-doped Pt/SiO2 catalysts for the selective regeneration of NADH and show that doping Pt/SiO2 with 10 at% Sn can deliver a selectivity of 90% (at full conversion) using H2 . We propose that this is a result of Sn disturbing the Pt ensemble, altering the mode of NAD + adsorption and directing the reduction to the 1, 4-position of the nicotinamide ring.