Dehydrogenative ester synthesis from enol ethers and water with a ruthenium complex catalyzing two reactions in synergy. Issue 4 (10th February 2022)

• Record Type: Journal Article
• Authors: Kar, Sayan; Luo, Jie; Rauch, Michael; Diskin-Posner, Yael; Ben-David, Yehoshoa; Milstein, David
• Is Part Of: Green chemistry. Volume 24:Issue 4(2022)
• Page Start: 1481
• Page End: 1487
• Publication Date: 2022-02-10
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/d1gc04574a
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : We report the dehydrogenative synthesis of esters via enol ether oxidation, using water as the formal oxidant, catalyzed by a newly developed ruthenium acridine-based PNP(Ph)-type complex. Abstract : We report the dehydrogenative synthesis of esters from enol ethers using water as the formal oxidant, catalyzed by a newly developed ruthenium acridine-based PNP(Ph)-type complex. Mechanistic experiments and density functional theory (DFT) studies suggest that an inner-sphere stepwise coupled reaction pathway is operational instead of a more intuitive outer-sphere tandem hydration–dehydrogenation pathway.