Transition‐Metal‐Mediated Glycosylation with Thioglycosides. Issue 14 (12th January 2022)

• Record Type: Journal Article
• Authors: Escopy, Samira; Demchenko, Alexei V.
• Is Part Of: Chemistry. Volume 28:Issue 14(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-01-12
• Subjects: activation -- glycans -- glycosylation -- thioglycosides; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.202103747
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: Thioglycosides are among the most common glycosyl donors that find broad application in the synthesis of glycans and glycoconjugates. However, the requirement for toxic and/or large access of activators needed for common glycosylations with thioglycosides remains a notable drawback. Due to the increased awareness of the chemical waste impact on the environment, synthetic studies have been driven by the goal of finding non‐toxic reagents. The main focus of this review is to highlight recent methods for thioglycoside activation that rely on transition metal catalysis. Abstract : Methods for thioglycoside activation that rely on transition metal catalysis are summarized in this review.