Biosupramolecular networks: Taking inspiration from nature to create powerful synthetic platforms. (February 2022)

• Record Type: Journal Article
• Authors: Watson, Emma E.; Winssinger, Nicolas
• Is Part Of: Current opinion in chemical biology. Volume 66(2022)
• Publication Date: 2022-02
• Subjects: Networks -- Molecular circuitry -- Chemistry of biomolecules -- Biosupramolecular chemistry; Bioorganic chemistry -- Periodicals; Biology -- Periodicals; Biochemistry -- Periodicals; Clinical biochemistry -- Periodicals; Biochemistry -- Periodicals; Chimie bio-organique -- Périodiques; Biologie -- Périodiques; 572.05
• DOI: 10.1016/j.cbpa.2021.102104
• Languages: English
• ISSNs: 1367-5931

Abstract

Abstract: Nature is predicated on the ability to process large number of parallel signals to produce specific downstream outputs. Biosupramolecular networks are beginning to allow such processing power in synthetic systems, particularly through harnessing the recognition power of biomolecules. Such systems can be summarised through the reductionist view of containing inputs, circuitry motifs and functional outputs, with each of these elements able to be readily combined in a modular approach. Through the inherent 'plug and play' nature of these systems the field continues to rapidly expand, providing a wealth of new smart diagnostic and therapeutic systems.