Creating a Health Utility Value for Birdshot Chorioretinopathy. (2nd January 2022)

• Record Type: Journal Article
• Authors: Sekaran, Anisha; Shamdas, Mohith; Barry, Robert J.; Denniston, Alastair K.; Murray, Philip I.
• Is Part Of: Ocular immunology and inflammation. Volume 30:Number 1(2022)
• Page Start: 73
• Page End: 80
• Publication Date: 2022-01-02
• Subjects: Birdshot chorioretinopathy -- quality of life -- time trade-off -- standard gamble -- EQ-5D-5L -- NEI VFQ-25; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2020.1799034
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose: To create a health utility value for birdshot chorioretinopathy (BCR) using Time Trade-Off (TTO) and Standard Gamble (SG) utilities. Method: Adult BCR patients completed TTO, SG, EQ-5D-5L, and NEI VFQ-25 questionnaires and underwent a detailed history and clinical examination. Results: A total of 28 BCR patients (9 M, 19 F; mean age 62 years, range 47–83) were included. There were 22 patients with a logMAR vision of 0.3 or better in both eyes. Mean TTO was 0.90 ± SD 0.18 (range 0.33–1.0) and mean SG was 0.94 ± SD 0.14 (range 0.5–1.0). TTO correlated with EQ-5D-5L index value ( p = .024) and NEI VFQ-25 composite score ( p = .015). Conclusions: Of 28 patients with BCR, 11 would trade remaining life (mean 5.4 years), and 6 would take a risk of immediate death (mean 28% risk), in return for perfect vision in both eyes for the rest of their life.