A comparison of the antimicrobial resistance of fecal Bacteroides isolates and assessment of the composition of the intestinal microbiotas of carbapenem-treated and non-treated persons from Belgium and Hungary. (February 2022)

• Record Type: Journal Article
• Authors: Sóki, József; Wybo, Ingrid; Wirth, Roland; Hajdú, Edit; Matuz, Mária; Burián, Katalin
• Is Part Of: Anaerobe. Volume 73(2022)
• Publication Date: 2022-02
• Subjects: Antibiotic resistance -- Bacteroides -- B. fragilis -- Carbapenems -- Microbiome; Anaerobic infections -- Periodicals; Anaerobic bacteria -- Periodicals; Bacterial diseases -- Periodicals; Computer network resources; Anaerobic protozoa -- Periodicals; 579.3
• DOI: 10.1016/j.anaerobe.2021.102480
• Languages: English
• ISSNs: 1075-9964

Abstract

Abstract: The antimicrobial susceptibilities of Bacteroides strains isolated from the feces of imipenem-treated patients from Belgium and Hungary were compared with those isolated from the normal microbiota from these two and five other European countries and assessed. Of the 10 antibiotics tested, highly significant differences were found with cefoxitin (decrease for Belgium and for this two and the five countries from the previous study), clindamycin (decrease for Belgium and for this two and the five countries from the previous study) and moxifloxacin (increase for Belgium and for this two and the five countries from the previous study) relative to normal microbiota strains reported earlier. Imipenem treatment brought about modest, but notable differences in the compositions of the microbiomes where there was less diversity in the treated group relative to the non-treated group. Highlights: Bacteroides strains from the feces of imipenem-treated and non-treated patients were isolated. Out of 10 antibiotics, cefoxitin, clindamycin, moxifloxacin, and tetracycline gave different resistance values between the above two groups of strains. Imipenem-treatment caused a decrease in the diversity of the patients' microbiomes.